We would like to inform you that, we have changed the name of our kits for TREC and TREC/KREC screening from SCREEN-ID to the new trade-marked name SPOT-it™ as of October 12, 2018. The products are identical and will carry the same product codes as previously. We hope that the change will not cause any confusion or inconveniences.
The SPOT-it™ neonatal screening kit for severe primary immunodeficiency diseases is an all-in-one system for the quantitation of T-cell specific TRECs (T-cell receptor excision circles) and/or B-cell specific KRECs (kappa-deleting recombination excision circles) as well as quality control markers (beta-actin) using commonplace quantitative real-time PCR (qPCR). The SPOT-it™ kit employs regular 3.2mm Guthrie card spots and features a Filter plate concept to rinse samples prior to analysis. The kit includes all necessary reagents pre-arranged in a set of Elution and qPCR plates and requires only two pipetting steps. (Figure 1